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Home Antibody All anti-FIG4 antibodies
UltraMAB

Anti-FIG4 GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA590525
  • Rabbit Polyclonal FIG4 Antibody
100ug 325 In Stock
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IHC(2)
IF(1)
ELISA(1)
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Also for FIG4 (NM_014845)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the N Terminus Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration0.72mg/ml
Guaranteed Application *ELISA, IHC, IF Suggested DilutionsWB: 1:500; ELISA: 1:100-1:2000; IHC: 1:300; IF: 1:25
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens FIG4 phosphoinositide 5-phosphatase (FIG4)
Alternative NameALS11; CMT4J; dJ249I4.1; KIAA0274; SAC3; YVS
Database LinkNP_055660
FunctionThe PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol-3,5-bisphosphate (PtdIns(3,5)P2). In vitro, hydrolyzes all three D5-phosphorylated polyphosphoinositide substrates in the order PtdIns(4,5)P2 > PtdIns(3,5)P2 > PtdIns(3,4,5)P3. Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

ELISA Image
ELISA: FIG4 Antibody
IHC Image
Immunohistochemistry: FIG4 Antibody - Most of the normal tissues displayed moderate to strong cytoplasmic positivity which was occasionally accompanied with nuclear staining. Malignant tissues exhibited in most cases moderate cytoplasmic immunoreactivity. Strong staining was observed in several tumors but was most prominent in colo-rectal and stomach cancers. Image and statement courtesy of the Human Protein Atlas (HPA).
IHC Image
Immunohistochemical staining of human duodenum shows strong positivity in glandular cells.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.
IF Image
Immunofluorescent staining of human cell line U-2 OS shows no positivity.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.

 

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