Homo sapiens fibroblast growth factor 5 (FGF5), transcript variant 1
Synonyms:
HBGF-5; Smag-82
Immunogen
Peptide with sequence C-PLSAPRKNTNSVK, from the C Terminus of the protein sequence according to NP_004455.2; NP_149134.1.
Buffer
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Clone Name
Isotype
Species Reactivity
Human
Concentration
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. (Protein A or G Sepharose)
Guaranteed Application *
WB
Suggested Dilutions
WB: 0.1-0.3ug/ml
Background
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq].
Related Pathway
MAPK signaling pathway
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