Home Antibody All anti-FGF1 antibodies
Also for FGF1 (NM_000800)
|This FGF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-30 amino acids from the N-terminal region of human FGF1.|
|Human (Predicted: Pig)
|WB, IHC, IF
||WB: 1:1000, IHC: 1:10~50, IF: 1:10~50
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.|
|This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
|Homo sapiens fibroblast growth factor 1 (acidic) (FGF1), transcript variant 1|
|AFGF; ECGF; ECGF-beta; ECGFA; ECGFB; FGF-1; FGF-alpha; FGFA; GLIO703; HBGF-1; HBGF1|
Entrez Gene 2246 Human
|FGF1 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis.|
|Secreted ProteinDruggable Genome MAPK signaling pathwayRegulation of actin cytoskeletonPathways in cancerMelanoma|
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Western blot analysis of FGF1 (arrow) using rabbit polyclonal FGF1 Antibody (N-term) (Cat.#TA302125). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FGF1 gene (Lane 2) (Origene Technologies).
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with FGF1 antibody (N-term) (Cat.#TA302125), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Confocal immunofluorescent analysis of FGF1 Antibody (N-term)(Cat#TA302125) with WiDr cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).