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Anti-FGB Antibody EPR3083


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against Fibrinogen beta chain (clone EPR3083 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417459) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of in human Fibrinogen beta chain was used as an immunogen.
Clone NameEPR3083 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:1000 - 1:2000; FC: 1:20; ICC/IF: 1:100 - 1:250
Predicted MW Explanation 56 kDa
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for IHC-P or IP.

Reference Data

Target NameHomo sapiens fibrinogen beta chain (FGB), transcript variant 1
Alternative NameHEL-S-78p
Database LinkNP_005132
Entrez Gene 2244 Human
Entrez Gene 110135 Mouse
Entrez Gene 24366 Rat
FunctionFibrinogen beta chain yields monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation. Conversion of fibrinogen to fibrin is triggered by thrombin, which cleaves fibrinopeptides A and B from alpha and beta chains, and thus exposes the N-terminal polymerization sites responsible for the formation of the soft clot. Defects in FGB are a cause of thrombophilia. Defects in FGB are a cause of congenital afibrinogenemia. This rare autosomal recessive disorder is characterized by bleeding that varies from mild to severe and by complete absence or extremely low levels of plasma and platelet fibrinogen (1).
Related PathwaySecreted ProteinDruggable Genome Complement and coagulation cascades

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-Fibrinopeptide B antibody [EPR3083]; All lanes : Anti-Fibrinopeptide B antibody [EPR3083] at 1/1000 dilution.Lane 1 : Human plasma lysate.Lane 2 : Human prostate lysate.Lane 3 : Rat platelet lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 56 kDa.
Immunocytochemistry/ Immunofluorescence - Anti-Fibrinopeptide B antibody [EPR3083]; Immunofluorescence analysis of Fibrinopeptide B in HeLa cells, using TA307248 at a dilution of 1/100.


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