Home Antibody All anti-FEZ2 antibodies
Also for FEZ2 (NM_001042548)
|FEZ2 antibody was raised against a 15 amino acid peptide from near the center of human FEZ2.|
|Human, Mouse, Rat
||ELISA, WB: 0.5 - 1 ug/ml, IF: 5 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens fasciculation and elongation protein zeta 2 (zygin II) (FEZ2), transcript variant 2|
|Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-z substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-z, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-z in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.|
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Western blot analysis of FEZ2 in 3T3 cell lysate with FEZ2 antibody at (A) 0.5, and (B) 1 ug/mL.
Immunofluorescence of human brain tissue using FEZ2 antibody at 5 ug/mL.