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Home Antibody All anti-FDPS antibodies

Anti-FDPS Antibody EPR4628

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307581 Rabbit monoclonal antibody against FDPS(clone EPR4628) 100ul $325 In Stock
LC427716 FDPS HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human FDPS was used as an immunogen.
Clone NameEPR4628 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; FC: 1:10 - 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for ICC or IP.

Reference Data

Target NameHomo sapiens farnesyl diphosphate synthase (FDPS), transcript variant 2
Alternative NameFPPS; FPS
Database LinkNP_001129293
Entrez Gene 2224 Human
FunctionFDPS is an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption (1).
Related PathwayDruggable Genome Terpenoid backbone biosynthesisMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - FDPS antibody [EPR4628]; All lanes : Anti-FDPS antibody [EPR4628] at 1/1000 dilution.Lane 1 : THP1 cell lysates.Lane 2 : HepG2 cell lysates.Lane 3 : Human fetal liver lysates.Predicted band size : 48 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - FDPS antibody [EPR4628]; TA307581 at 1/100 dilution staining FDPS in Human kidney by Immunohistochemistry, Paraffin-embedded tissue.
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