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Home Antibody All anti-FDPS antibodies

Anti-FDPS Antibody EPR4628

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307581
  • Rabbit monoclonal antibody against FDPS(clone EPR4628)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC427716) , 20ug
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for FDPS (NM_001135821)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human FDPS was used as an immunogen.
Clone NameEPR4628 IsotypeTissue culture supernatant
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; FC: 1:10 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for ICC or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for ICC or IP.

Reference Data

Target NameHomo sapiens farnesyl diphosphate synthase (FDPS), transcript variant 2
Alternative NameFPPS; FPS
Database LinkNP_001129293
FunctionFDPS is an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption (1).
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - FDPS antibody [EPR4628]; All lanes : Anti-FDPS antibody [EPR4628] at 1/1000 dilution.Lane 1 : THP1 cell lysates.Lane 2 : HepG2 cell lysates.Lane 3 : Human fetal liver lysates.Predicted band size : 48 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - FDPS antibody [EPR4628]; TA307581 at 1/100 dilution staining FDPS in Human kidney by Immunohistochemistry, Paraffin-embedded tissue.

 

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