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Home Antibody All anti-FCGR3A antibodies

Anti-FCGR3A Antibody EPR4333

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SKU Description Amount Price Availability*  
TA307690
  • Rabbit monoclonal antibody against CD16a(clone EPR4333)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400194) , 20ug Explanation
100ul 325 In Stock
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WB(1)
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Also for FCGR3A (NM_000569)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human CD16a was used as an immunogen.
Clone NameEPR4333 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:50000 - 1:20000; ICC: 1:100 - 1:250
Predicted MW Explanation 29 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens Fc fragment of IgG, low affinity IIIa, receptor (CD16a) (FCGR3A), transcript variant 1
Alternative NameCD16; CD16A; FCG3; FCGR3; FCGRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; IMD20
Database LinkNP_000560
Entrez Gene 2214 Human
Entrez Gene 304966 Rat
FunctionCD16a is involved in the removal of antigen-antibody complexes from the circulation, as well as other antibody-dependent responses. The receptor encoded by CD16a is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide. Mutations in CD16a have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia (1).
Related PathwaySecreted ProteinES Cell Differentiation/IPSTransmembrane Natural killer cell mediated cytotoxicityFc gamma R-mediated phagocytosisSystemic lupus erythematosus

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - CD16 antibody [EPR4333]; All lanes : Anti-CD16 antibody [EPR4333] at 1/50000 dilution.Lane 1 : U937 cell lysate.Lane 2 : THP-1 cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : K562 cell lysate.Lane 5 : C6 cell lysate.Lane 6 : Raw264.7 cell lysate.Lane 7 : PC-12 cell lysates .Lysates/proteins at 10 ug per lane.Predicted band size : 29 kDa.Observed band size : 45 kDa .

 

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