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Anti-FBXO2 Antibody EPR7328(2)
Also for FBXO2 (NM_012168)
|A synthetic peptide corresponding to residues in human FBXO2 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, FC
||WB: 1:10000 - 1:50000; FC: 1:10 - 1:100
Preservative: 0.01% Sodium azide
Constituents: 48% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for ICC,IHC-P or IP.
|Homo sapiens F-box protein 2 (FBXO2)|
|FBG1; Fbs1; FBX2; NFB42; OCP1|
Entrez Gene 26232 Human
Entrez Gene 230904 Mouse
Entrez Gene 85273 Rat
|FBXO2 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO2 belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state (1). |
|Druggable Genome Ubiquitin mediated proteolysis|
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Western blot - Anti-FBXO2 antibody [EPR7328(2)]; All lanes : Anti-FBXO2 antibody [EPR7328(2)] at 1/10000 dilution.Lane 1 : Human fetal brain lysate.Lane 2 : NIH 3T3 cell lysate.Lane 3 : Neuro 2a cell lysate.Lane 4 : Human fetal lung lysate.Lane 5 : HT29 cell lysate.Lane 6 : U87 MG cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution.Predicted band size : 33 kDa.
Other-Anti-FBXO2 antibody [EPR7328(2)](TA310485); Equilibrium disassociation constant (KD)..
Flow Cytometry - Anti-FBXO2 antibody [EPR7328(2)]; Flow cytometric analysis of permeabilized NIH 3T3 cells labelling FBXO2 with TA310485 at 1/10 (red) or a rabbit IgG negative control antibody (green).