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Anti-FBP2 Antibody EPR7436
Also for FBP2 (NM_003837)
|A synthetic peptide corresponding to residues near the C-terminus of human FBP2 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
|WB, ASSAY, IHC
||WB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for IP.
|Homo sapiens fructose-1,6-bisphosphatase 2 (FBP2)|
|FBP2, also known as Fructose-1,6-bisphosphatase isozyme 2, belongs to the FBPase class 1 family (1). It is a gluconeogenesis regulatory enzyme that catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate (2). FBP2 is subject to complex allosteric regulation. The enzyme can assume an active R-state, or an inactive T-state. Intermediate conformations may exist. AMP acts as allosteric inhibitor. Fructose-2,6-biphosphate acts as competitive inhibitor (1).|
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Western blot - Anti-FBP2 antibody [EPR7436]; All lanes : Anti-FBP2 antibody [EPR7436] at 1/1000 dilution.Lane 1 : Human skeletal muscle lysate.Lane 2 : Rat muscle lysate.Lane 3 : Mouse muscle lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled Goat anti Rabbit IgG at 1/2000 dilution.Predicted band size : 37 kDa.
Other-Anti-FBP2 antibody [EPR7436](ab131253); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FBP2 antibody [EPR7436]; Immunohistochemical analysis of paraffin embedded Human muscle tissue labelling FBP2 with ab131253 antibody at 1/50 dilution.