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Home Antibody All anti-FBP1 antibodies

Anti-FBP1 Antibody EPR4620

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307699
  • Rabbit monoclonal antibody against FBP1(clone EPR4620)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424655) , 20ug
100ul $325 3-7 Days
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WB(1)
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Also for FBP1 (NM_000507)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human FBP1 was used as an immunogen.
Clone NameEPR4620 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; ICC: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IHC-P.

Reference Data

Target NameHomo sapiens fructose-1,6-bisphosphatase 1 (FBP1), transcript variant 1
Alternative NameFBP
Database LinkNP_000498
FunctionFBP1 (Fructose-1,6-bisphosphatase 1) is a gluconeogenesis regulatory enzyme that catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate (1). FBP1 catalyzes the removal of phosphate-1 from fructose 1,6-bisphosphate to produce fructose 6-phosphate, an important precursor in various biosynthetic pathways. It is a key, rate-controlling enzyme of gluconeogenesis, an important metabolic pathway that allows the cells to synthesize glucose and grow on non-carbohydrate carbon sources, such as glycerol, organic acids and amino acids (2). Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis (1).
Related Pathway

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WB Image
Western blot - FBP1 antibody [EPR4620]; All lanes : Anti-FBP1 antibody [EPR4620] at 1/1000 dilution.Lane 1 : Human stomach lysate.Lane 2 : Human fetal liver lysate.Lane 3 : MCF7 lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 37 kDa.

 

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