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Home Antibody All anti-F11R antibodies

Anti-F11R TRUEMAB Antibody Clone OTI6E11

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA506034 F11R mouse monoclonal antibody, clone OTI6E11 (formerly 6E11) 100ul
30ul
$379 In Stock
LC403392 F11R HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF506034 Carrier-free (BSA/glycerol-free) F11R mouse monoclonal antibody, clone OTI6E11 (formerly 6E11) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IF(1)

OriGene Data

ImmunogenFull length human recombinant protein of human F11R(NP_653087) produced in HEK293T cell.
Clone NameClone OTI6E11 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IF Suggested Dilutions WB 1:4000, IF 1:100,
Predicted MW Explanation 29.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens F11 receptor (F11R), transcript variant 5
Alternative NameJAM, KAT, JAM1, JAMA, JCAM, CD321, JAM-1, JAM-A, PAM-1
Database LinkNP_653087
Entrez Gene 50848 Human
FunctionTight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008].
Related PathwayTransmembraneDruggable Genome Cell adhesion molecules (CAMs)Tight junctionLeukocyte transendothelial migrationEpithelial cell signaling in Helicobacter pylori infection

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY F11R (RC200004, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-F11R.
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Anti-F11R mouse monoclonal antibody (TA506034) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY F11R(RC200004).
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