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Anti-F11R TRUEMAB Antibody Clone OTI6E11
TrueMAB Antibodies - Made against Authentic Protein Antigens
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Also for F11R (NM_144504)
|Full length human recombinant protein of human F11R(NP_653087) produced in HEK293T cell.|
||WB 1:4000, IF 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens F11 receptor (F11R), transcript variant 5|
|JAM, KAT, JAM1, JAMA, JCAM, CD321, JAM-1, JAM-A, PAM-1|
Entrez Gene 50848 Human
|Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008].|
|TransmembraneDruggable Genome Cell adhesion molecules (CAMs)Tight junctionLeukocyte transendothelial migrationEpithelial cell signaling in Helicobacter pylori infection|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY F11R (RC200004, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-F11R.
Anti-F11R mouse monoclonal antibody (TA506034) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY F11R(RC200004).