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Home Antibody All anti-F11 antibodies

Anti-F11 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308541
  • Rabbit Polyclonal antibody to Factor XI (coagulation factor XI)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400043) , 20ug
100ul 325 3-7 Days
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WB(1)
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Also for F11 (NM_000128)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 282 of Human F11
Clone Name IsotypeIgG
Species ReactivityHuman Concentration0.55mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens coagulation factor XI (F11)
Alternative NameFXI
Database LinkNP_000119
FunctionThis gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq]
Related Pathway
Hemostasis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample(30 ug of whole cell lysate) A:293T (anti-F11 antibody diluted at 1:1000)

 

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