Home Antibody All anti-Ezh2 antibodies
Also for Ezh2 (NM_001203247)
|Synthetic peptide mapping to the N-terminus of rat Ezh2|
|Human, mouse, rat
|100 µg (0.5 mg/ml) affinity purified rabbit anti- EZH2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.|
|Homo sapiens enhancer of zeste homolog 2 (Drosophila) (EZH2), transcript variant 3|
|ENX-1; ENX1; EZH1; EZH2b; KMT6; KMT6A; WVS; WVS2|
Entrez Gene 2146 Human
Entrez Gene 14056 Mouse
Entrez Gene 312299 Rat
|Enhancer of zeste homolog 2 (Ezh2) is a member of the Polycomb group (PcG). The PcG proteins are involved in maintaining the silenced state of several developmentally regulated genes and contribute to the maintenance of cell identity, cell cycle regulation, and oncogenesis. Enhancer of zeste homolog 2 (Ezh2) contains four conserved regions including domain I, domain II, and a cysteine-rich amino acid stretch that precedes the carboxy-terminal SET domain. Ezh2 also plays a role as primary effector and as a mediator of tumorigenesis.|
|Transcription FactorsDruggable Genome |
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Western blot analysis of Ezh2 using rat kidney tissue lysate.