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Home Antibody All anti-ESR1 antibodies

Anti-ESR1 Antibody Polyclonal

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA319645
  • Rabbit Polyclonal ESR1 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400046) , 20ug Explanation
100ug $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenESR1 antibody was raised against an 18 amino acid peptide near the center of human ESR1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsELISA, WB: 1 - 2 ug/ml
Predicted MW Explanation Predicted: 65 kDa Observed: 62 kDa
BufferESR1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification ESR1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens estrogen receptor 1 (ESR1), transcript variant 1
Alternative NameER; Era; ESR; ESRA; ESTRR; NR3A1
Database LinkNP_000116
Entrez Gene 2099 Human
Entrez Gene 13982 Mouse
Entrez Gene 24890 Rat
FunctionESR1 Antibody: Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors (1). Estrogen receptors, including ESR1, also known as ER-alpha and ESR2 (ER-beta), contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. ESR1 is a widely expressed nuclear protein and serves as a strong activator of estrogen responsive genes (1,2). Phosphorylation of serines 104 and 106, located in the N-terminal transcription activation function-1 domain (AF-1), plays a large role in regulating ER alpha activity (3).
Related PathwayNuclear Hormone ReceptorTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of ESR1 in rat brain tissue lysate with ESR1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
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