OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431.
[anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780.
[SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052
[anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210.
[NPR3] View All Citations >>
Home All anti-EIF6 antibodies
Anti-EIF6 Antibody EPR6512(B)
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
Also for EIF6 (NM_001267810)
Homo sapiens eukaryotic translation initiation factor 6 (EIF6), transcript variant 6 b(2)gcn; CAB; eIF-6; EIF3A; ITGB4BP; p27(BBP); p27BBP A synthetic peptide corresponding to residues in human eIF-6 was used as an immunogen. Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
EPR6512(B)
Human, Mouse, Rat
(Protein A or G Sepharose )
WB, IHC
WB: 1:10.000 - 50,000; IHC 1:100 - 250; IP: 1:100 - 500;
Hemidesmosomes are structures that link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. eIF-6 binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. It is insoluble and found in both the nucleus and cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits (1).
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
WB Image
Western blot analysis on (A) HeLa, (B) RAW 264.7, (C) K562, (D) 293T, and (E) HepG2 cell lysates using anti-eIF-6 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human colonic adenocarcinoma using anti-eIF-6 RabMAb.
Conjugation Services
HRP
Biotin
PE
FITC
DyLight® 488
DyLight® 550
DyLight® 594
DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
