Home All anti-EIF4G2 antibodies
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Also for EIF4G2 (NM_001042559)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 204 of Human EIF4G2|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens eukaryotic translation initiation factor 4 gamma, 2 (EIF4G2), transcript variant 2|
|AAG1; DAP5; NAT1; P97|
|Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq]|
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Sample(30 ug of whole cell lysate) A:A431 (anti-EIF4G2 antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using EIF4G2 (anti-EIF4G2 antibody) antibody at 1:100 dilution.