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Home Antibody All anti-EGFR antibodies

Anti-EGFR Antibody E114


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA303484 Rabbit monoclonal antibody against EGF Receptor(E114) 100ul $325 In Stock
LC404515 EGFR HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues near C-terminus of human EGF receptor was used as immunogen.
Clone NameE114 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsIHC-P: Use at an assay dependent concentration; WB: 1:5000; ICC: 1:10; IP: 1:10
Predicted MW Explanation 170 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens epidermal growth factor receptor (EGFR), transcript variant 3
Alternative NameERBB; ERBB1; HER1; mENA; NISBD2; PIG61
Database LinkNP_958440
Entrez Gene 1956 Human
Entrez Gene 13649 Mouse
Entrez Gene 24329 Rat
FunctionThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq].
Related PathwayStem cell relevant signaling - JAK/STAT signaling pathwayProtein KinaseSecreted ProteinES Cell Differentiation/IPSTransmembraneAdult stem cellsCancer stem cellsDruggable Genome MAPK signaling pathwayErbB signaling pathwayCalcium signaling pathwayCytokine-cytokine receptor interactionEndocytosisDorso-ventral axis formationMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-EGFR antibody [E114]; Anti-EGFR antibody [E114] + A431 cell lysate.Predicted band size : 170 kDa.

IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EGFR antibody [E114]; Immunohistochemical analysis of human cervical carcinoma using TA303484.

IF Image
Immunocytochemistry - Anti-EGFR antibody [E114]; Immunofluorescent staining of A431 cells using TA303484.


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