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Anti-EBI3 Antibody DNT27
Also for EBI3 (NM_015766)
||0.5-1mg/ml (lot dependent)
|Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
|Mus musculus Epstein-Barr virus induced gene 3 (Ebi3)|
Entrez Gene 50498 Mouse
|The monoclonal antibody DNT27 reacts with mouse Epstein-Barr Virus-induced gene 3 (EBI3). EBI3 is a 34 kDa soluble protein first identified in B cells that is upregulated after Epstein-Barr virus infection. EBI3 can exist as a homodimer and also heterodimerizes with IL-27α (p28, IL-30) to form the cytokine IL-27. IL-27 is produced most abundantly by dendritic cells and macrophages with some recent reports of expression in NKT cells. Recently, a complex of EBI3 and the p35 subunit of IL-12, called IL-35, has been reported to be produced by regulatory T cells.|
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Mouse IL-27 Recombinant Protein (lane 1) and mouse bone marrow-derived dendritic cells stimulated with LPS (lane 2) or left untreated (lane 3) were analyzed by SDS-PAGE followed by immunoblotting with 5 ug/ml of Anti-Mouse EBI3 (IL-27 subunit) Purified. Bands were visualized with Anti-Rat IgG HRP .