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Anti-EBF1 Antibody EPR4183
Also for EBF1 (NM_024007)
|A synthetic peptide corresponding to residues in human EBF1 was used as an immunogen.|
||Tissue culture supernatant
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000
|Does not react with Rat. Is unsuitable for Flow Cyt,ICC,IHC-P or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens early B-cell factor 1 (EBF1), transcript variant 2|
|COE1; EBF; O/E-1; OLF1|
|The early B-cell factors (EBF) are a family of highly conserved DNA-binding transcription factors (1). They are involved in the differentiation and maturation of several cell lineages including B-progenitor lymphoblasts, neuronal precursors, and osteoblast progenitors (1). EBF1 is a transcriptional activator that belongs to the COE family (2). It interacts with ZNF423 and ZNF521, preventing EBF1 from binding to DNA and activating target genes (2). During B-cell development, EBF1 is required for the expression of Pax5, an essential factor for the production of antibody-secreting cells (1). EBF1 also controls nervous system development and olfactory receptor gene expression (3). In addition, it is expressed in mouse adipocytes (3).|
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Western blot - EBF1 antibody [EPR4183]; All lanes : Anti-EBF1 antibody [EPR4183] at 1/1000 dilution.Lane 1 : Raji cell lysate .Lane 2 : Daudi cell lysate.Lane 3 : 3T3-LI cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 64 kDa.