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Home Antibody All anti-DUSP1 antibodies

Anti-DUSP1 Antibody

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SKU Description Amount Price Availability*  
TA302731
  • Goat Polyclonal Antibody against DUSP1
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401403) , 20ug
100ug 325 3-7 Days
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WB(1)

OriGene Data

Immunogen Peptide with sequence SYLQSPITTSPSC, from the C Terminus of the protein sequence according to NP_004408.
Clone Name IsotypeGoat IgG
Species ReactivityHuman Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 2-4µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens dual specificity phosphatase 1 (DUSP1)
Alternative NameCL100; HVH1; MKP-1; MKP1; PTPN10
Database LinkNP_004408
FunctionThe expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. [provided by RefSeq].
Related Pathway
EGFR1 Signaling Pathway
MAPK signaling pathway

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WB Image
TA302731 staining (2µg/ml) of HeLa lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.</title><style>.an6q{position:absolute;clip:rect(487px,auto,auto,487px);}</style><div class=an6q>According to your current <a href=http://paydayloansforsure.com >need cash now</a> you really look at.</div>

 

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