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Anti-DTNBP1 Antibody EPR7042(B)
Also for DTNBP1 (NM_032122)
| A synthetic peptide corresponding to residues on the C-terminus in human Dysbindin was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; FC: 1:100 - 1:500; ICC/IF: 1:50 - 1:100
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for IHC-P.
|Homo sapiens dystrobrevin binding protein 1 (DTNBP1), transcript variant 1|
|BLOC1S8; DBND; HPS7; My031; SDY|
|Dysbindin is a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in Dysbindin are associated with Hermansky-Pudlak syndrome type 7. It may also be associated with schizophrenia (1).|
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Western blot - Anti-Dysbindin antibody [EPR7042(B)]; All lanes : Anti-Dysbindin antibody [EPR7042(B)] at 1/1000 dilution.Lane 1 : SH-SY5Y cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : HepG2 cell lysate .Lane 4 : 293T cell lysate .Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 39 kDa.
Other-Anti-Dysbindin antibody [EPR7042(B)](TA310429); Equilibrium disassociation constant (KD)..