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Anti-DSC3 Antibody EPR7486


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against DSC3
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human DSC3 was used as an immunogen.
Clone NameEPR7486 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, FC Suggested DilutionsWB: 1:10000 - 1:50000; FC: 1:10 - 1:100; ICC/IF: 1:100 - 1:250
Predicted MW Explanation 100 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for IHC-P or IP.

Reference Data

Target NameHomo sapiens desmocollin 3 (DSC3), transcript variant Dsc3a
Alternative NameCDHF3; DSC; DSC1; DSC2; DSC4; HT-CP
Database LinkNP_001932
Entrez Gene 1825 Human
Entrez Gene 13507 Mouse
Entrez Gene 307563 Rat
FunctionDSC3 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation (1).
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-Desmocollin 3 antibody [EPR7486]; All lanes : Anti-Desmocollin 3 antibody [EPR7486] at 1/10000 dilution.Lane 1 : A431 lysates.Lane 2 : Human skin lysates.Lane 3 : Human espophagus lysates.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 100 kDa.
Other-Anti-Desmocollin 3 antibody [EPR7486](TA310425); Equilibrium disassociation constant (KD)..
Flow Cytometry - Anti-Desmocollin 3 antibody [EPR7486]; TA310425 at 1/10 dilution staining Desmocollin 3 in permeabilized A431 cells by Flow cytometry (red) compared with a rabbit IgG negative control (green).


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