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Anti-DPYSL2 PHOSPHO Antibody EPR7876
Also for DPYSL2 (NM_001386)
|A phospho specific peptide corresponding to residues surrounding Threonine 514 of human CRMP-2 was used as an immunogen. This antibody only detects CRMP-2 phosphorylated at Threonine 514.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for IHC-P or IP.
|Homo sapiens dihydropyrimidinase-like 2 (DPYSL2), transcript variant 2|
|CRMP-2; CRMP2; DHPRP2; DRP-2; DRP2; N2A3; ULIP-2; ULIP2|
|CRMP-2 is a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. CRMP-2 promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This protein has been implicated in multiple neurological disorders, and hyperphosphorylation of CRMP-2 may play a key role in the development of Alzheimer's disease (1). |
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Western blot - Anti-CRMP2 (phospho T514) antibody [EPR7876]; All lanes : Anti-CRMP2 (phospho T514) antibody [EPR7876] at 1/1000 dilution.Lane 1 : Human fetal brain lysate, untreated .Lane 2 : Human fetal brain lysate, treated with Lambda Phosphatase.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 62 kDa.
Other-Anti-CRMP2 (phospho T514) antibody [EPR7876](ab129066); Equilibrium disassociation constant (KD)..