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UltraMAB

DOCK2 UltraMAB Antibody, Clone UMAB142

UltraMAB™ Antibodies - Validated with 10K Protein Chip

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Specifications Citations Related Products Product Documents
SKU Description Datasheet Price Availability*  
UM800039
  • DOCK2 mouse monoclonal antibody,clone UMAB142, 100 ul
468 In Stock Add to Shopping Cart
UM870039
  • DOCK2 mouse monoclonal antibody,clone UMAB142, 30 ul
$120 In Stock Add to Shopping Cart
WB(2)
IHC(5)
Gene NameHomo sapiens dedicator of cytokinesis 2 (DOCK2)
SynonymsFLJ46592; KIAA0209
ImmunogenHuman recombinant protein fragment corresponding to amino acids 1544-1830 of human DOCK2 (NP_004937) produced in E.coli.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone NameClone UMAB142 IsotypeIgG2a
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000, IHC 1:150,
BackgroundThe protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells, predominantly in the peripheral blood leukocytes, and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration, through the activation of RAC. Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes. These mutant mice also exhibited long-term survival of allografts, suggesting that this gene may be a target for controlling transplant rejection. [provided by RefSeq, Oct 2011].

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of  Jurkat cell lysate (35ug) by using anti-DOCK2 monoclonal antibody.
WB Image
Western blot analysis of RPMI8226 cell lysate (35ug) by using anti-DOCK2 monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-DOCK2 mouse monoclonal antibody. (UM800039)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-DOCK2 mouse monoclonal antibody. (UM800039)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-DOCK2 mouse monoclonal antibody. (UM800039)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-DOCK2 mouse monoclonal antibody. (UM800039)
IHC Image
Immunohistochemical staining of paraffin-embedded Human tonsil using anti-DOCK2 mouse monoclonal antibody. (UM800039)

 

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