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Home Antibody All anti-DMP1 antibodies

Anti-DMP1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305886
  • Goat Anti-DMP1 Antibody
100ug 325 3-7 Days
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WB(1)
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Also for DMP1 (NM_001079911)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenPeptide with sequence C-ENSEQANTQDSG, from the internal region of the protein sequence according to NP_004398.1; NP_001073380.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1-3ug/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens dentin matrix acidic phosphoprotein 1 (DMP1), transcript variant 2
Alternative NameARHP; ARHR; DMP-1
Database LinkNP_001073380
Entrez Gene 1758 Human
FunctionDentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq].
Related PathwaySecreted Protein

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA305886 (1ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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