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Home Antibody All anti-DLX4 antibodies

Anti-DLX4 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA301565 Rabbit Polyclonal Antibody against BP1 100ul $325 3-7 Days
LC403346 DLX4 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(2)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide made specifically to the human BP1 protein sequence (between residues 1-60).There is no homology with the peptide sequences used for immunogen of this antibody and the DLX4 or DLX7 proteins.
Clone Name IsotypeIgG
Species Reactivityhuman Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1: 1000, IHC: 1:50-1: 100
Predicted MW Explanation 26kDa
BufferTris-citrate/phosphate, pH 7-8, 0.1% sodium Azide
Purification Immunogen affinity purified

Reference Data

Target NameHomo sapiens distal-less homeobox 4 (DLX4), transcript variant 1
Alternative NameBP1; DLX7; DLX8; DLX9
Database LinkNP_612138
Entrez Gene 1748 Human
FunctionDLX (Distal-less) genes are essential for early development. BP1 (beta protein 1) is a homeodomain-containing isoform of DLX4. Strong BP1 expression is seen in placenta and kidney tissue, with no expression found in any other tissue (1). This protein has been shown to be activated in 80% of invasive ductal breast tumors and is associated with breast cancer progression ( 2, 3). It is also expressed in the bone marrows of 63% of acute myeloid leukemia (AML) patients (4). In addition, BP1 plays a role in globin gene regulation by repressing the beta- globin gene (1).
Related PathwayTranscription Factors

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Detection of MDA-MB-231 cell lysates
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Immunoprecipitation: Antibody diluted 1:5,000 2. BP1-specific band after immunoprecipitation of 850 ug of cell extract using anti-BP1 (NB100-481) antibody diluted 1:1,000 3. Negative control for IP in lane 2: cell extract incubated with 50ul of Protein A/G beads.
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Immunohistochemistry - Top Panel: BP1 antibody detected in breast cancer cells. Bottom Panel: Staining of normal breast cancer cells.
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