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Home Antibody All anti-DISP1 antibodies

Anti-DISP1 Antibody Polyclonal

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SKU Description Amount Price Availability*  
TA320062 Rabbit Polyclonal DISP1 Antibody 100ug $325 In Stock
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenDISP1 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human DISP1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferDISP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification DISP1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens dispatched homolog 1 (Drosophila) (DISP1)
Alternative NameDISPA
Database LinkNP_116279
Entrez Gene 84976 Human
Entrez Gene 68897 Mouse
FunctionDISP1 Antibody: DISP1 is the mammalian homolog of the Drosophila Dispatched segment-polarity gene and a key regulator of the Hedgehog (Hh) signaling pathway during embryonic development. DISP1 is required to move Shh from site of synthesis during embryogenesis; mutations in the gene result in lethality at mid-gestation and prevents specification of ventral cell types in the neural tube. Recent results have shown that DISP1 mediates the basolateral secretion of Shh and regulates growth of mammalian long bones through the control of Ihh.
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of DISP1 in 3T3 cell lysate with DISP1 antibody at (A) 1 and (B) 2 ug/mL.
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Immunohistochemistry of DISP1 in human kidney tissue with DISP1 antibody at 2.5 ug/mL.
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Immunofluorescence of DISP1 in human kidney tissue with DISP1 antibody at 20 ug/mL.
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