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Home Antibody All anti-DDX60 antibodies

Anti-DDX60 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319959
  • Rabbit Polyclonal DDX60 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC413632) , 20ug
100ug 325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenDDX60 antibody was raised against a 17 amino acid synthetic peptide near the center of human DDX60.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 - 2 ug/ml, IF: 20 ug/ml
BufferDDX60 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification DDX60 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 (DDX60)
Alternative NameFLJ10787; FLJ20035
Database LinkNP_060101
FunctionDDX60 Antibody: DDX60 is a DEXD/H Box RNA helicase and the human homolog of the S. cerevisiae Ski2, a cofactor of RNA exosome. Expression of DDX60 increases after viral infection and binds to endogenous RIG-I, a cytoplasmic viral RNA sensor, as well as other RIG-I-like receptors such as MDA5 and LGP2. These proteins activate TBK1 and IKK-e, signaling IRF3 and NF-kB-responsive genes in the innate immune response pathway. DDX60 is required for the RIG-I- or MDA5-dependent response to viral infection, but is dispensable for TLR3-mediated signaling.
Related Pathway

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WB Image
Western blot analysis of DDX60 in A20 cell lysate with DDX60 antibody at (A) 1 and (B) 2 ug/mL.
IF Image
Immunofluorescence of DDX60 in A20 cells with DDX60 antibody at 20 ug/mL.

 

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