Home Antibody All anti-DDC antibodies
Also for DDC (NM_001082971)
|Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH|
|bovine, dog, guinea porcine, human, rabbit, rat, sheep
||0.5~1.0 mg/ml (Lot Dependent)
|100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. |
|Homo sapiens dopa decarboxylase (aromatic L-amino acid decarboxylase) (DDC), transcript variant 1|
|The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]. |
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Western blot of 5 Î¼g of bovine adrenal medulla lysate showing specific immunolabeling of the ~55k DOPA decarboxylase protein.