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Anti-DCTN2 Antibody EPR5095

WB(1)

IF(1)

Gene Name Homo sapiens dynactin 2 (p50) (DCTN2), transcript variant 2 Synonyms: DCTN50; DYNAMITIN; RBP50 Immunogen A synthetic peptide corresponding to residues in human DCTN2 was used as an immunogen. Buffer Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt. Clone Name EPR5095 Isotype Species Reactivity Human Concentration Purification (Protein A or G Sepharose) Guaranteed Application * WB, IF Suggested Dilutions WB: 1:10,000 - 50,000; IP: 1:10 - 100; Background DCTN2 is a subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kDa. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. DCTN2 contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place (1). Related Pathway Cell cycle

Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • DCTN2 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • DCTN2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Dctn2 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • DCTN2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Dctn2 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones Related cDNA Clones

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)