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Home Antibody All anti-DCTN2 antibodies

Anti-DCTN2 Antibody EPR5095

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310398
  • Rabbit Monoclonal antibody against DCTN2
100ul 325 3-7 Days
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WB(1)
IF(1)
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Also for DCTN2 (NM_006400)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human DCTN2 was used as an immunogen.
Clone NameEPR5095 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC/IF: 1:100 - 1:250; IP: 1:10 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt.
Purification pH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens dynactin 2 (p50) (DCTN2), transcript variant 1
Alternative NameDCTN50; DYNAMITIN; HEL-S-77; RBP50
Database LinkNP_006391
Entrez Gene 10540 Human
FunctionDCTN2 is a subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kDa. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. DCTN2 contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place (1).
Related Pathway
Cell cycle

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Dynamitin antibody [EPR5095]; All lanes : Anti-Dynamitin antibody [EPR5095] at 1/1000 dilution.Lane 1 : MCF7 cell lysate.Lane 2 : A375 cell lysate.Lane 3 : Saos2 cell lysate.Lane 4 : SH SY5Y cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 44 kDa.Observed band size : 44 kDa.
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-Dynamitin antibody [EPR5095]; Immunofluorescence analysis of Dynamitin in SH-SY5Y cells, using TA310398 at a dilution of 1/100.

 

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