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Home Antibody All anti-DAXX antibodies

Anti-DAXX Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305964
  • Rabbit Polyclonal Daxx Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC427986) , 20ug
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for DAXX (NM_001141969)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenDaxx antibody was raised against a peptide corresponding to amino acids near the carboxy-terminus of human Daxx.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 ug/ml, ICC: 10 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Antibody is DEAE purified

Reference Data

Target NameHomo sapiens death-domain associated protein (DAXX), transcript variant 1
Alternative NameBING2; DAP6; EAP1
Database LinkNP_001135441
FunctionApoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family. A novel DD-containing molecule was recently cloned from mouse, human and monkey and designated Daxx. Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway. Daxx is widely expressed in fetal and adult human and mouse tissues indicating its important function in Fas signaling pathways.
Related Pathway
MAPK signaling pathway
TGF Beta Signaling Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Daxx in 293 total cell lysate with Dax antibody at 1 mg/mL.
IF Image
Immunocytochemistry of DAXX in HeLa cells with DAXX antibody at 10 ug/mL.

 

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