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Home Antibody All anti-CYP2E1 antibodies

Anti-CYP2E1 TRUEMAB Antibody Clone OTI9E6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA500735 anti-CYP2E1 (Cytochrome P450 2E1) mouse monoclonal antibody, clone OTI9E6 (formerly 9E6) 100ul 325
In Stock
LC400264 CYP2E1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500735 Carrier-free (BSA/glycerol-free) CYP2E1 mouse monoclonal antibody, clone OTI9E6 (formerly 9E6) 100ug $450 3-4 weeks
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Also for CYP2E1 (NM_000773)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human CYP2E1 (NP_000764) produced in HEK293T cell.
Clone NameClone OTI9E6 IsotypeIgG1
Species ReactivityHuman Concentration0.74 mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:500, IHC 1:50, IF 1:100,
Predicted MW Explanation 56.8 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens cytochrome P450, family 2, subfamily E, polypeptide 1 (CYP2E1)
Alternative NameCPE1; CYP2E; P450-J; P450C2E
Database LinkNP_000764
Entrez Gene 1571 Human
FunctionThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
Related PathwayTransmembraneP450Druggable Genome Arachidonic acid metabolismLinoleic acid metabolismMetabolism of xenobiotics by cytochrome P450Drug metabolism - cytochrome P450Metabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP2E1 (RC213502, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP2E1 .

IHC Image
Immunohistochemical staining of paraffin-embedded breast tissue within the normal limits using anti-CYP2E1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500735, Dilution 1:50)

IF Image
Anti-CYP2E1 mouse monoclonal antibody (TA500735) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CYP2E1 (RC213502).

IF Image
Immunofluorescent staining of HepG2 cells using anti-CYP2E1 mouse monoclonal antibody (TA500735).


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