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Home Antibody All anti-CYP19A1 antibodies

Anti-CYP19A1 Antibody EPR6293

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310386
  • Rabbit Monoclonal antibody against Cytochrome P450 17A1 (CYP19A1)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400031) , 20ug
100ul $325 3-7 Days
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WB(1)
IF(1)
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Also for CYP19A1 (NM_000103)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Cytochrome P450 17A1 was used as an immunogen.
Clone NameEPR6293 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; ICC/IF: 1:100 - 1:250
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IHC-P.

Reference Data

Target NameHomo sapiens cytochrome P450, family 19, subfamily A, polypeptide 1 (CYP19A1), transcript variant 1
Alternative NameARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM
Database LinkNP_000094
FunctionCytochrome P450 17A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. It localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in Cytochrome P450 17A1 are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia (1).
Related Pathway

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WB Image
Western blot - Anti-Cytochrome P450 17A1 antibody [EPR6293]; All lanes : Anti-Cytochrome P450 17A1 antibody [EPR6293] at 1/1000 dilution.Lane 1 : Human adrenal gland lysate.Lane 2 : SK-OV-3 lysate.Lane 3 : HeLa lysate.Lane 4 : Jurkat lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 57 kDa.Observed band size : 55 kDa .
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-Cytochrome P450 17A1 antibody [EPR6293]; TA310386, at 1/100 dilution, staining Cytochrome P450 17A1 in Hela cells by Immunofluorescence.

 

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