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Home Antibody All anti-CXCR6 antibodies

Anti-CXCR6 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306016
  • Rabbit Polyclonal Bonzo Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401965) , 20ug
100ug 325 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenBonzo antibody was raised against a peptide corresponding to amino acids near the amino terminus of human Bonzo/STRL33. The sequence of this peptide differs from those of African green monkey and pig-tailed macaque by one or two amino acids, respectively,.
Clone Name IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens chemokine (C-X-C motif) receptor 6 (CXCR6)
Alternative NameBONZO; CD186; STRL33; TYMSTR
Database LinkNP_006555
FunctionHuman immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV coreceptors. An orphan G protein-coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as HIV and SIV coreceptor (1-4). Bonzo/STRL33 serves as coreceptor for SIV, HIV-2 and HIV-1. The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes.
Related Pathway
Cytokine-cytokine receptor interaction
Signaling by GPCR

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WB Image
Western blot analysis of Bonzo in human spleen tissue lysate in the absence (lane A) or presence (lane B) of peptide with Bonzo antibody (NT2) at 1:500 dilution. Below: Immunohistochemistry of Bonzo in human spleen cells with Bonzo antibody at 20 µg/ml.
IHC Image
Immunohistochemistry of Bonzo in human spleen cells with Bonzo antibody at 20 ug/ml.

 

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