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Anti-CXCL1 Antibody EPR4902
Also for CXCL1 (NM_001511)
|A synthetic peptide corresponding to residues in human GRO alpha was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:10000 - 1:50000
|Does not react with Mouse, Rat. Is unsuitable for ICC/IF,IHC-P or IP.|
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Is unsuitable for ICC/IF,IHC-P or IP.
|Homo sapiens chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (CXCL1), transcript variant 1|
|FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1|
Entrez Gene 2919 Human
|Chemokines are a group of small (approximately 8 to 14 kDa), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CXC chemokines such as GRO alpha are further subdivided into ELR and non-ELR types based on the presence or absence of a glu-leu-arg sequence adjacent and N terminal to the CXC motif. ELR types are chemotactic for neutrophils, while non-ELR types are chemotactic for lymphocytes (1).|
|Secreted ProteinDruggable Genome Cytokine-cytokine receptor interactionChemokine signaling pathwayNOD-like receptor signaling pathwayEpithelial cell signaling in Helicobacter pylori infection|
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Western blot - Anti-GRO alpha antibody [EPR4902]; Anti-GRO alpha antibody [EPR4902] at 1/10000 dilution + Human GRO alpha recombinant protein at 0.01 ug.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 11 kDa.