A synthetic phospho-peptide corresponding to residues surrounding Tyr228 of human p120 Catenin was used as immunogen. The antibody only detects p120 Catenin phosphorylated on Tyrosine 228. Predicted to cross-react with mouse, based on sequence homology.
Buffer
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and althernative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. [provided by RefSeq].
Related Pathway
Adherens junction
EGFR1 Signaling Pathway
Wnt Signaling Pathway
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Western blot analysis on HeLa cell lysate using anti- Phospho-p120 Catenin (Y228) RabMAb (TA303472), dilution 1:5,00-20,000. Cell lysates were (1) untreated, (2) treated with Pervanandate, or (3) treated with Phosphatase.
