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Home Antibody All anti-CTCF antibodies

Anti-CTCF Antibody EPR7313

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310367
  • Rabbit Monoclonal antibody against CTCF
100ul 325 3-7 Days
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WB(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human CTCF was used as an immunogen.
Clone NameEPR7313 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:1000
Predicted MW Explanation 83 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens CCCTC-binding factor (zinc finger protein) (CTCF), transcript variant 2
Alternative NameMRD21
Database LinkNP_001177951
Entrez Gene 10664 Human
Entrez Gene 13018 Mouse
Entrez Gene 83726 Rat
FunctionCTCF is a member of the BORIS + CTCF family and is a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in CTCF have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors (1).
Related PathwayTranscription Factors

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-CTCF antibody [EPR7313]; All lanes : Anti-CTCF antibody [EPR7313] at 1/1000 dilution.Lane 1 : U937 cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : MDA-MB-435 cell lysate.Lane 4 : 293T cell lysate.Lane 5 : Caco-2 cell lysate.Lane 6 : RAW 264.7 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 83 kDa.
Assay Image
Other-Anti-CTCF antibody [EPR7313](TA310367); Equilibrium disassociation constant (KD)..

 

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