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Home Antibody All anti-CRADD antibodies

Anti-CRADD Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305944
  • Rabbit Polyclonal RAIDD Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401253) , 20ug
100ug $325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenRAIDD antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human RAIDD .
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500 - 1:1000
BufferPBS containing 0.02% sodium azide.
Purification Antibody is DEAE purified

Reference Data

Target NameHomo sapiens harakiri, BCL2 interacting protein (HRK), transcript variant 1
Alternative NameDP5; HARAKIRI
Database LinkNP_003797
FunctionApoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain (DD)-containing receptors, TNFR1 and Fas. The death signals are transduced by a group of DD-containing adapter molecules. A novel cell death adapter was recently identified by two independent groups and designated RAIDD (RIP-associated ICH-1/CED-3-homologous protein with DD) and CRADD (caspase and RIP adapter with DD)1,RAIDD contains a DD and a CARD (for caspase recruitment domain) which interact with RIP and caspase, respectively, to transduce death signals. RAIDD is constitutively expressed in many tissues and mediates apoptosis caused by Fas and TNFR-1.
Related Pathway
Apoptosis

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WB Image
Western blot analysis of RAIDD in HeLa total cell lysate with RAIDD antibody at 1 ug/ml.
IHC Image
Immunohistochemistry of RAIDD in human kidney tissue with RAIDD antibody at 10 ug/ml.

 

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