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Home Antibody All anti-CDKN1B antibodies

Anti-CDKN1B Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302712
  • Goat Polyclonal Antibody against CDKN1B
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401318) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for CDKN1B (NM_004064)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

Immunogen Peptide with sequence C-EQTPKKPGLRRRQT, from the C Terminus of the protein sequence according to NP_004055.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat, Cow, Dog Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:32,000. WB: 1-3µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B)
Alternative NameCDKN4; KIP1; MEN1B; MEN4; P27KIP1
Database LinkNP_004055
Entrez Gene 1027 Human
Entrez Gene 12576 Mouse
Entrez Gene 83571 Rat
Entrez Gene 403429 Dog
FunctionThis gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq].
Related PathwayDruggable Genome ErbB signaling pathwayCell cyclePathways in cancerProstate cancerChronic myeloid leukemiaSmall cell lung cancerMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA302712 (1µg/ml) staining of Human Breast lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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