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Anti-CDH10 Antibody EPR5115
Also for CDH10 (NM_001190450)
|A synthetic peptide corresponding to residues in the cytoplasmic domain in human Cadherin-10 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; FC: 1:10 - 1:100
|Preservative: 0.01% Sodium azide|
Constituents: 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for ICC/IF,IHC-P or IP.
|Homo sapiens cadherin 10, type 2 (T2-cadherin) (CDH10), transcript variant 2|
|Cadherin-10 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance (1).|
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Western blot - Anti-cadherin 10 antibody [EPR5115]; All lanes : Anti-cadherin 10 antibody [EPR5115] at 1/1000 dilution.Lane 1 : Human fetal brain lysate.Lane 2 : U-87 MG lysate.Lane 3 : Human fetal lung lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution.Predicted band size : 88 kDa.
Flow Cytometry - Anti-cadherin 10 antibody [EPR5115]; Flow cytometric analysis of permeabilised U-87 MG cells labelling cadherin 10 with ab134137 at 1/10 dilution (red) or rabbit IgG negative (green).