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Home Antibody All anti-CDC16 antibodies

Anti-CDC16 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319762 Rabbit Polyclonal APC6 Antibody 100ug $325 3-7 Days
LC421501 CDC16 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for CDC16 (NM_001078645)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenAPC6 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human APC6.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
BufferAPC6 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification APC6 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens cell division cycle 16 (CDC16), transcript variant 2
Alternative NameANAPC6; APC6; CUT9
Database LinkNP_001072113
Entrez Gene 8881 Human
Entrez Gene 69957 Mouse
FunctionAPC6 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC6 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. While little is known of APC6, it has been shown to interact with and is stabilized by CDC26 through an intermolecular TPR mimic composed of one helix from each protein.
Related PathwayDruggable Genome Cell cycleOocyte meiosisUbiquitin mediated proteolysisProgesterone-mediated oocyte maturation

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of APC6 in human liver tissue lysate with APC6 antibody at (A) 1 and (B) 2 ug/mL.

IHC Image
Immunohistochemistry of APC6 in human liver tissue with APC6 antibody at 5 ug/mL.

IF Image
Immunofluorescence of APC6 in human liver tissue with APC6 antibody at 20 ug/mL.


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