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Home Antibody All anti-CD8A antibodies

Anti-CD8A Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302180
  • Rabbit Polyclonal Antibody against CD8A (N-term)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403530) , 20ug Explanation
100ug 325 3-7 Days
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WB(2)
IHC(1)
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Also for CD8A (NM_171827)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenThis CD8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-88 amino acids from the N-terminal region of human CD8A.
Clone Name IsotypeRabbit Ig
Species ReactivityHuman Concentration0.25 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000, IHC: 1:10~50
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.

Reference Data

Target NameHomo sapiens CD8a molecule (CD8A), transcript variant 2
Alternative NameCD8; Leu2; MAL; p32
Database LinkNP_741969
Entrez Gene 925 Human
FunctionThe CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Related PathwaySecreted ProteinES Cell Differentiation/IPSTransmembraneAdult stem cellsDruggable Genome Cell adhesion molecules (CAMs)Antigen processing and presentationHematopoietic cell lineageT cell receptor signaling pathwayPrimary immunodeficiency

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of anti-CD8A Antibody (N-term) (Cat.#TA302180) in Hela cell line lysates (35ug/lane). CD8A(arrow) was detected using the purified Pab.
WB Image
Western blot analysis of CD8A(arrow) using rabbit polyclonal CD8A Antibody (N-term) (Cat.#TA302180). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CD8A gene (Lane 2) (Origene Technologies).
IHC Image
Formalin-fixed and paraffin-embedded human tonsil tissue reacted with CD8A Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

 

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