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 Home All anti-CD3G antibodies

Anti-CD3G Antibody EPR4517

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SKU Description Amount Price Availability*  
TA307757
  • Rabbit monoclonal antibody against CD3 gamma(clone EPR4517)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400019) , 20ug
 100ul $325 In Stock
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
 30ul
$100
$50*		 In Stock
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* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues at the C-terminus of human CD3 gamma was used as an immunogen.
Clone NameEPR4517 IsotypeRabbit IgG
Species ReactivityHuman, Mouse Concentration
Guaranteed Application *WB, IHC Suggested DilutionsICC: 1:500 - 1,000, IHC: 1:250 - 500, IP: 1:10 - 100, WB: 1:10,000 - 50,000,
BufferStore at -20 C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Reference Data

Target NameHomo sapiens CD3g molecule, gamma (CD3-TCR complex) (CD3G)
Alternative NameCD3-GAMMA; T3G
Database LinkNP_000064
FunctionCD3 is composed of five invariant polypeptide chains that associate to form three dimers. The five invariant chains of CD3 are labeled gamma, delta, epsilon, zeta, and eta (3). CD3 forms complex with the T cell antigen receptor (TCR) (1). Antigen binding to the TCR leads to IL-2 secretion via activation of a tyrosine phosphorylation pathway and a phospholipase C (PLC) pathway, in turn activating protein kinase C (1,2). Defects in this protein are associated with T cell immunodeficiency (4).
Related Pathway
Hematopoietic cell lineage

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WB Image
Western blot analysis on (A) Jurkat and (B) mouse thymus lysates using anti-CD3 gamma RabMAb .
IHC Image
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD3 gamma RabMAb .

 

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