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Anti-CD28 Antibody JJ319
Also for CD28 (NM_013121)
||0.5-1mg/ml (lot dependent)
||Flow, Functional Assay, IP
|Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
|Rattus norvegicus Cd28 molecule (Cd28)|
Entrez Gene 25660 Rat
|The JJ319 monoclonal antibody reacts with the rat CD28 molecule, expressed by thymocytes, mature T cells, and a subset of NK cells. CD28 is a ligand for CD80 (B7-1) and CD86 (B7-2) and is a potent costimulator of T cells. Signaling through CD28 augments IL-2 and IL-2 receptor expression as well as cytotoxicity of CD3-activated T cells. No reactivity of JJ319 is observed on mouse T cells.|
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Staining of Lou Rat splenocytes with 0.5 ug Mouse IgG1 Isotype Control Purified (open histogram) or 0.5 ug Anti-Rat CD28 Purified (filled histogram) followed by Anti-Mouse IgG FITC . Total viable cells were used for analysis.