UltraMAB Antibodies - Validated with 10K Protein Chip
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-CD1C mouse monoclonal antibody. (UM500042)
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-CD1C mouse monoclonal antibody. (UM500042)
OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-CD1C mouse monoclonal antibody (UM500042). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification.
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul
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OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-CD1C mouse monoclonal antibody (UM500042). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification.
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