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Home Antibody All anti-CCR8 antibodies

Anti-CCR8 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305990
  • Rabbit Polyclonal CCR8 Antibody
100ug 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenCCR8 antibody was raised against a peptide corresponding to amino acids 183 to 201 of human CCR8, which locate in the second extracellular loop.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 1:500 - 1:1000
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens chemokine (C-C motif) receptor 8 (CCR8)
Alternative NameCC-CKR-8; CCR-8; CDw198; CKRL1; CMKBR8; CMKBRL2; CY6; GPRCY6; TER1
Database LinkNP_005192
FunctionCCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1, and ChemR1. The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains. CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.
Related Pathway
Cytokine-cytokine receptor interaction
Signaling by GPCR

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WB Image
Western blot analysis of CCR8 in human spleen lysate with CCR8 antibody at 1:500 dilution.

 

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