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Anti-CCR8 Antibody E76
Also for CCR8 (NM_005201)
|A synthetic peptide corresponding to residues near C-terminus of human CKR8 was used as immunogen. The antibody does not cross-react with other G-protein coupled receptor 1 family members.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:500; ICC: 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|IgG fraction (Protein A or G Sepharose)
|Homo sapiens chemokine (C-C motif) receptor 8 (CCR8)|
|CC-CKR-8; CCR-8; CDw198; CKRL1; CMKBR8; CMKBRL2; CY6; GPRCY6; TER1|
|This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq]. |
Cytokine-cytokine receptor interaction
Signaling by GPCR
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Western blot - CCR8 antibody [E76]; Anti-CCR8 antibody [E76] at 1/500 dilution + Jurkat cell lysate.Predicted band size : 41 kDa.Observed band size : 45 kDa .