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Home Antibody All anti-CBLC antibodies

Anti-CBLC TRUEMAB Antibody clone 4E3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA505093
  • CBLC mouse monoclonal antibody,clone 4E3
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402148) , 20ug Explanation
100ul 325 In Stock
CF505093
  • Carrier-free (BSA/glycerol-free) CBLC mouse monoclonal antibody,clone 4E3
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
FC(1)
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Also for CBLC (NM_012116)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 244-474 of human CBLC(NP_036248) produced in HEK293T cell.
Clone Nameclone 4E3 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, FC Suggested Dilutions WB 1:500, FLOW 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens Cbl proto-oncogene C, E3 ubiquitin protein ligase (CBLC), transcript variant 1
Alternative NameCBL-3; CBL-SL; RNF57
Database LinkNP_036248
Entrez Gene 23624 Human
FunctionThis gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012].
Related Pathway
EGFR1 Signaling Pathway
Jak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CBLC (RC205130, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CBLC.
FC Image
HEK293T cells transfected with either RC205130 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-CBLC antibody(TA505093), and then analyzed by flow cytometry.

 

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