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Anti-CBLC TRUEMAB Antibody clone 4E3
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for CBLC (NM_012116)
|Human recombinant protein fragment corresponding to amino acids 244-474 of human CBLC(NP_036248) produced in HEK293T cell.|
|| WB 1:500, FLOW 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens Cbl proto-oncogene C, E3 ubiquitin protein ligase (CBLC), transcript variant 1|
|CBL-3; CBL-SL; RNF57|
Entrez Gene 23624 Human
|This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]. |
EGFR1 Signaling Pathway
Jak-STAT signaling pathway
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CBLC (RC205130, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CBLC.
HEK293T cells transfected with either RC205130 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-CBLC antibody(TA505093), and then analyzed by flow cytometry.