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Home Antibody All anti-CBL antibodies

Anti-CBL Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302756
  • Goat Polyclonal Antibody against CBL
100ug 325 3-7 Days
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WB(1)

OriGene Data

Immunogen Peptide with sequence C-REFVSISSPAHVAT, from the C Terminus of the protein sequence according to NP_005179.2.
Clone Name IsotypeGoat IgG
Species ReactivityMouse Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1-3µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameMus musculus Casitas B-lineage lymphoma (Cbl)
Alternative Name4732447J05Rik; c-Cbl; Cbl-2
Database LinkNP_031645
FunctionThe cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq].
Related Pathway

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WB Image
TA302756 staining (2µg/ml) of 3T3 lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

 

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