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Home Antibody All anti-CASP7 antibodies

Anti-CASP7 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301617
  • Mouse Monoclonal Antibody against Caspase 7
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC409592) , 20ug
100ul 325 3-7 Days
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WB(1)
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Also for CASP7 (NM_033339)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull-length recombinant human Caspase 7 protein
Clone Name IsotypeIgG1 kappa
Species Reactivityhuman, rat, mouse ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1: 1000
BufferAscitic fluid and 0.1% sodium azide
Purification Ascites

Reference Data

Target NameHomo sapiens caspase 7, apoptosis-related cysteine peptidase (CASP7), transcript variant c
Alternative NameCASP-7; CMH-1; ICE-LAP3; LICE2; MCH3
Database LinkNP_203125
FunctionCaspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase-9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
Related Pathway
Apoptosis
MAPK signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western Blot: Caspase 7 Antibody (Mch3 1-1-11) TA301617 - HeLa whole cell lysate.

 

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